First of all, what kind of EPROMs/Flash are you using?
Secondly, cart connector #46 is A21 and you'd have to solder directly onto it.
MAD-1 Pin 1 goes to EPROM #2 /OE
MAD-1 Pin 16 goes to EPROM #1 /OE
If only using 1 EPROM connect /OE to MAD-1 Pin 4
Obviously (not tested) the MAD-1 only decodes A20/A22 leaving A21 disconnected since A19 being the highest address line here for EPROMs.
Since your EPROM/FLash has A21, you'd have to rewire MAD-1 Pin 12 and 13 probably.
Edited: 04/14/2017
at 03:20 PM
by Ice Man