You're being the polar opposite of helpful here, Fx3.
I wasn't even aware Nestopia used Direct3D (is it faster than DirectDraw or something?). I know of several emulators that let you switch between DirectDraw and Direct3D, so maybe Nestopia has a similar option? I'm not at my home computer right now, so I can't check. (1.40 works fine for me, BTW.)
If all else fails, you could try reinstalling your video card drivers. Given the incredible vagueness of that error message, that's about all the advice I can give you...